Hepatic protection from chemical injury by isoflurane

Isoflurane inhibits oxidative metabolism of halothane. Because hepatotoxicity of chemicals may be associated with their metabolism, whether isoflurane can protect the liver against chemical injury was investigated. Hepatic injury was produced in female F344 rats by a 30-minute exposure to 250 ppm of...

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Veröffentlicht in:	Anesthesia and analgesia 1988-09, Vol.67 (9), p.860-867
Hauptverfasser:	GIL, F, FISEROVA-BERGEROVA, V, ALTMAN, N. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Anesthetics. Neuromuscular blocking agents Animals Aspartate Aminotransferases - blood Biological and medical sciences Carbon Tetrachloride - adverse effects Chemical and Drug Induced Liver Injury Female Isoflurane - therapeutic use L-Iditol 2-Dehydrogenase - blood Liver - enzymology Liver Diseases - prevention & control Medical sciences Neuropharmacology Pharmacology. Drug treatments Rats Rats, Inbred F344
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