IL6 receptor 358 Ala variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis

To test the hypothesis that patients with amyotrophic lateral sclerosis (ALS) inheriting the common interleukin 6 receptor (IL6R) coding variant (Asp Ala, rs2228145, C allele) have associated increases in interleukin 6 (IL6) and IL6R levels in serum and CSF and faster disease progression than noncar...

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Veröffentlicht in:	Neurology : neuroimmunology & neuroinflammation 2019-11, Vol.6 (6), p.e631
Hauptverfasser:	Wosiski-Kuhn, Marlena, Robinson, Mac, Strupe, Jane, Arounleut, Phonepasong, Martin, Matthew, Caress, James, Cartwright, Michael, Bowser, Robert, Cudkowicz, Merit, Langefeld, Carl, Hawkins, Gregory A, Milligan, Carol
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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