Antitumour activity and adverse reactions of combined treatment with chitosan and doxorubicin in tumour-bearing mice

We examined the antitumour activity and adverse reactions, such as myelotoxicity, gastrointestinal toxicity and body‐weight loss, of the cancer chemotherapy drug doxorubicin when given with chitosan in sarcoma 180‐bearing mice. Intraperitoneally administered doxorubicin (5 mg kg−1) given on days 1 a...

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