Direct Binding and Activation of Protein Kinase C Isoforms by Aldosterone and 17β-Estradiol

Protein kinase C (PKC) is a signal transduction protein that has been proposed to mediate rapid responses to steroid hormones. Previously, we have shown aldosterone directly activates PKCα whereas 17β-estradiol activates PKCα and PKCδ; however, neither the binding to PKCs nor the mechanism of action...

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Veröffentlicht in:	Molecular endocrinology (Baltimore, Md.) Md.), 2007-11, Vol.21 (11), p.2637-2650
Hauptverfasser:	Alzamora, Rodrigo, Brown, Laura R, Harvey, Brian J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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