Efficacy of Glyburide/Metformin Tablets Compared with Initial Monotherapy in Type 2 Diabetes

Many patients with type 2 diabetes fail to achieve or maintain the American Diabetes Association’s recommended treatment goal of glycosylated hemoglobin levels. This multicenter, double-blind trial enrolled patients with type 2 diabetes who had inadequate glycemic control [glycosylated hemoglobin A1...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2003-08, Vol.88 (8), p.3598-3604
Hauptverfasser:	Garber, Alan J., Donovan, Daniel S., Dandona, Paresh, Bruce, Simon, Park, Jong-Soon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Blood Glucose - metabolism Body Weight - drug effects Body Weight - physiology Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Double-Blind Method Drug Combinations Female Fructosamine - blood Glyburide - adverse effects Glyburide - therapeutic use Glycated Hemoglobin A - metabolism Humans Hypoglycemic Agents - adverse effects Hypoglycemic Agents - therapeutic use Insulin - blood Male Metformin - adverse effects Metformin - therapeutic use Middle Aged Postprandial Period - physiology
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Beschreibung
Zusammenfassung:	Many patients with type 2 diabetes fail to achieve or maintain the American Diabetes Association’s recommended treatment goal of glycosylated hemoglobin levels. This multicenter, double-blind trial enrolled patients with type 2 diabetes who had inadequate glycemic control [glycosylated hemoglobin A1C (A1C), >7% and
ISSN:	0021-972X 1945-7197
DOI:	10.1210/jc.2002-021225