Influence of Process Parameters on the Precipitation of Organic Nanoparticles by Drowning-Out
Ethylcellulose (the organic substance), ethanol (the solvent) and water (the nonsolvent) are chosen as a model system for the production of uniform nanoparticles by drowning-out. Experiments carried out under various operating conditions show that many process parameters, such as the type of stirrer...
Gespeichert in:
| Veröffentlicht in: | Chemical engineering research & design 1997-02, Vol.75 (2), p.237-244 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 244 |
|---|---|
| container_issue | 2 |
| container_start_page | 237 |
| container_title | Chemical engineering research & design |
| container_volume | 75 |
| creator | Plasari, E. Grisoni, P.H. Villermaux, J. |
| description | Ethylcellulose (the organic substance), ethanol (the solvent) and water (the nonsolvent) are chosen as a model system for the production of uniform nanoparticles by drowning-out. Experiments carried out under various operating conditions show that many process parameters, such as the type of stirrer and the stirring speed, the temperature and the solvent–nonsolvent ratio, have practically no influence on the formation of ethylcellulose particles. On the other hand, the ethylcellulose concentration in the initial alcoholic solution seems to be the most important parameter controlling the particle size distribution. A comparison is made between experimental results and predictions of classical nucleation theories or aggregative growth models. |
| doi_str_mv | 10.1205/026387697523507 |
| format | Article |
| fullrecord | <record><control><sourceid>elsevier_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1205_026387697523507</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0263876297715223</els_id><sourcerecordid>S0263876297715223</sourcerecordid><originalsourceid>FETCH-LOGICAL-c420t-c30482f5855a685f374091ffa16279f6bdbf39365786e53c7c134f566486bdae3</originalsourceid><addsrcrecordid>eNp1kDtPAzEQhF2ARAjUtC5oj_hxflyJwitSRFJAiU4bxw5GF9_JdkD59zgKokCiWmnmm93VIHRFyQ1lREwIk1wr2SjBuCDqBI0OSlUkdobOU_oghFBV6xF6mwXX7WwwFvcOL2NvbEp4CRG2NtuYcB9wfrfFscYPPkP2RSnoIm4geIOfIfQDxOxNZxNe7fFd7L-CD5tqscsX6NRBl-zlzxyj14f7l-lTNV88zqa388rUjOTKcFJr5oQWAqQWjquaNNQ5oJKpxsnVeuV4w6VQWlrBjTKU105IWevigeVjNDnuNbFPKVrXDtFvIe5bStpDI-2fRkri-pgYIBnoXIRgfPqNFZpzKgvWHDFbvv_0NrbJ-ENba18Kye269_-e-AYiC3Q2</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Influence of Process Parameters on the Precipitation of Organic Nanoparticles by Drowning-Out</title><source>Elsevier ScienceDirect Journals</source><creator>Plasari, E. ; Grisoni, P.H. ; Villermaux, J.</creator><creatorcontrib>Plasari, E. ; Grisoni, P.H. ; Villermaux, J.</creatorcontrib><description>Ethylcellulose (the organic substance), ethanol (the solvent) and water (the nonsolvent) are chosen as a model system for the production of uniform nanoparticles by drowning-out. Experiments carried out under various operating conditions show that many process parameters, such as the type of stirrer and the stirring speed, the temperature and the solvent–nonsolvent ratio, have practically no influence on the formation of ethylcellulose particles. On the other hand, the ethylcellulose concentration in the initial alcoholic solution seems to be the most important parameter controlling the particle size distribution. A comparison is made between experimental results and predictions of classical nucleation theories or aggregative growth models.</description><identifier>ISSN: 0263-8762</identifier><identifier>DOI: 10.1205/026387697523507</identifier><identifier>CODEN: CERDEE</identifier><language>eng</language><publisher>Rugby: Elsevier B.V</publisher><subject>Applied sciences ; Chemical engineering ; Crystallization, leaching, miscellaneous separations ; drowning-out ; ethylcellulose ; Exact sciences and technology ; nanoparticles ; precipitation ; process parameters</subject><ispartof>Chemical engineering research & design, 1997-02, Vol.75 (2), p.237-244</ispartof><rights>1997 The Institution of Chemical Engineers</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-c30482f5855a685f374091ffa16279f6bdbf39365786e53c7c134f566486bdae3</citedby><cites>FETCH-LOGICAL-c420t-c30482f5855a685f374091ffa16279f6bdbf39365786e53c7c134f566486bdae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1205/026387697523507$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,777,781,786,787,3538,23912,23913,25122,27906,27907,45977</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2633316$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Plasari, E.</creatorcontrib><creatorcontrib>Grisoni, P.H.</creatorcontrib><creatorcontrib>Villermaux, J.</creatorcontrib><title>Influence of Process Parameters on the Precipitation of Organic Nanoparticles by Drowning-Out</title><title>Chemical engineering research & design</title><description>Ethylcellulose (the organic substance), ethanol (the solvent) and water (the nonsolvent) are chosen as a model system for the production of uniform nanoparticles by drowning-out. Experiments carried out under various operating conditions show that many process parameters, such as the type of stirrer and the stirring speed, the temperature and the solvent–nonsolvent ratio, have practically no influence on the formation of ethylcellulose particles. On the other hand, the ethylcellulose concentration in the initial alcoholic solution seems to be the most important parameter controlling the particle size distribution. A comparison is made between experimental results and predictions of classical nucleation theories or aggregative growth models.</description><subject>Applied sciences</subject><subject>Chemical engineering</subject><subject>Crystallization, leaching, miscellaneous separations</subject><subject>drowning-out</subject><subject>ethylcellulose</subject><subject>Exact sciences and technology</subject><subject>nanoparticles</subject><subject>precipitation</subject><subject>process parameters</subject><issn>0263-8762</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><recordid>eNp1kDtPAzEQhF2ARAjUtC5oj_hxflyJwitSRFJAiU4bxw5GF9_JdkD59zgKokCiWmnmm93VIHRFyQ1lREwIk1wr2SjBuCDqBI0OSlUkdobOU_oghFBV6xF6mwXX7WwwFvcOL2NvbEp4CRG2NtuYcB9wfrfFscYPPkP2RSnoIm4geIOfIfQDxOxNZxNe7fFd7L-CD5tqscsX6NRBl-zlzxyj14f7l-lTNV88zqa388rUjOTKcFJr5oQWAqQWjquaNNQ5oJKpxsnVeuV4w6VQWlrBjTKU105IWevigeVjNDnuNbFPKVrXDtFvIe5bStpDI-2fRkri-pgYIBnoXIRgfPqNFZpzKgvWHDFbvv_0NrbJ-ENba18Kye269_-e-AYiC3Q2</recordid><startdate>19970201</startdate><enddate>19970201</enddate><creator>Plasari, E.</creator><creator>Grisoni, P.H.</creator><creator>Villermaux, J.</creator><general>Elsevier B.V</general><general>Institution of Chemical Engineers</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19970201</creationdate><title>Influence of Process Parameters on the Precipitation of Organic Nanoparticles by Drowning-Out</title><author>Plasari, E. ; Grisoni, P.H. ; Villermaux, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-c30482f5855a685f374091ffa16279f6bdbf39365786e53c7c134f566486bdae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Applied sciences</topic><topic>Chemical engineering</topic><topic>Crystallization, leaching, miscellaneous separations</topic><topic>drowning-out</topic><topic>ethylcellulose</topic><topic>Exact sciences and technology</topic><topic>nanoparticles</topic><topic>precipitation</topic><topic>process parameters</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Plasari, E.</creatorcontrib><creatorcontrib>Grisoni, P.H.</creatorcontrib><creatorcontrib>Villermaux, J.</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>Chemical engineering research & design</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Plasari, E.</au><au>Grisoni, P.H.</au><au>Villermaux, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Process Parameters on the Precipitation of Organic Nanoparticles by Drowning-Out</atitle><jtitle>Chemical engineering research & design</jtitle><date>1997-02-01</date><risdate>1997</risdate><volume>75</volume><issue>2</issue><spage>237</spage><epage>244</epage><pages>237-244</pages><issn>0263-8762</issn><coden>CERDEE</coden><abstract>Ethylcellulose (the organic substance), ethanol (the solvent) and water (the nonsolvent) are chosen as a model system for the production of uniform nanoparticles by drowning-out. Experiments carried out under various operating conditions show that many process parameters, such as the type of stirrer and the stirring speed, the temperature and the solvent–nonsolvent ratio, have practically no influence on the formation of ethylcellulose particles. On the other hand, the ethylcellulose concentration in the initial alcoholic solution seems to be the most important parameter controlling the particle size distribution. A comparison is made between experimental results and predictions of classical nucleation theories or aggregative growth models.</abstract><cop>Rugby</cop><pub>Elsevier B.V</pub><doi>10.1205/026387697523507</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0263-8762 |
| ispartof | Chemical engineering research & design, 1997-02, Vol.75 (2), p.237-244 |
| issn | 0263-8762 |
| language | eng |
| recordid | cdi_crossref_primary_10_1205_026387697523507 |
| source | Elsevier ScienceDirect Journals |
| subjects | Applied sciences Chemical engineering Crystallization, leaching, miscellaneous separations drowning-out ethylcellulose Exact sciences and technology nanoparticles precipitation process parameters |
| title | Influence of Process Parameters on the Precipitation of Organic Nanoparticles by Drowning-Out |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T09%3A41%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-elsevier_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Influence%20of%20Process%20Parameters%20on%20the%20Precipitation%20of%20Organic%20Nanoparticles%20by%20Drowning-Out&rft.jtitle=Chemical%20engineering%20research%20&%20design&rft.au=Plasari,%20E.&rft.date=1997-02-01&rft.volume=75&rft.issue=2&rft.spage=237&rft.epage=244&rft.pages=237-244&rft.issn=0263-8762&rft.coden=CERDEE&rft_id=info:doi/10.1205/026387697523507&rft_dat=%3Celsevier_cross%3ES0263876297715223%3C/elsevier_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_els_id=S0263876297715223&rfr_iscdi=true |