Endotoxin induces glutathione reductase activity in lungs of mice

Glutathione reductase catalyzes the NADPH-dependent conversion of glutathione disulfide to glutathione and helps protect the lung from injury by reactive oxygen. In animals allowed to breathe nearly 100% oxygen, the activities of other antioxidants in the lung can be induced by treatment with endoto...

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Veröffentlicht in:	Pediatric research 1994-03, Vol.35 (3), p.311-315
Hauptverfasser:	HAMBURG, D. C, TONOKI, H, WELTY, S. E, GESKE, R. S, MONTGOMERY, C. A, HANSEN, T. N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Biological and medical sciences Cell physiology Effects of physical and chemical agents Endotoxins - pharmacology Female Fundamental and applied biological sciences. Psychology Glutathione Reductase - biosynthesis Glutathione Reductase - genetics Lung - drug effects Lung - enzymology Lung Injury Male Mice Molecular and cellular biology Oxygen - toxicity Reactive Oxygen Species - metabolism Reactive Oxygen Species - toxicity RNA, Messenger - genetics RNA, Messenger - metabolism
Online-Zugang:	Volltext
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