Indomethacin fails to induce ulceration in the gastrointestinal tract of newborn and suckling rats

Little is known about the role of oral prostaglandins and maintenance of intestinal epithelial cell membrane integrity in suckling animals. The presence of prostaglandins in milk suggests that they may have potential cytoprotective effects. Thus, experiments were performed to determine whether indom...

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Veröffentlicht in:	Pediatric research 1986-07, Vol.20 (7), p.598-601
Hauptverfasser:	BEDRICK, A. D, HOLTZAPPLE, P. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences Fundamental and applied biological sciences. Psychology Indomethacin - adverse effects Indomethacin - metabolism Intestinal Diseases - chemically induced Intestinal Diseases - pathology Prostaglandins - pharmacology Prostaglandins. Arachidonic acid metabolites Rats Rats, Inbred Strains Ulcer - chemically induced Ulcer - pathology Vertebrates: endocrinology
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