Genetics and the etiology of childhood cancer

A consideration of the world-wide incidences of childhood cancer and of hereditary subgroups leads to the conclusion that two successive mutations can initiate cancer cells and that such cells usually proceed to develop into detectable cancers in a period of time which is short compared with the tim...

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Veröffentlicht in:	Pediatric research 1976-05, Vol.10 (5), p.513-517
1. Verfasser:	Knudson, Jr, A G
Format:	Artikel
Sprache:	eng
Schlagworte:	Child Eye Neoplasms - genetics Humans Kidney Neoplasms - genetics Leukemia - genetics Lymphoma - genetics Models, Biological Mutation Neoplasms - etiology Neoplasms - genetics Neuroblastoma - genetics Oncogenic Viruses Retinoblastoma - genetics Wilms Tumor - genetics
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