Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivoin HLA-DR1 transgenic mice

Professional antigen-presenting cells, such as dendritic cells, macrophages and B cells have been implicated in the pathogenesis of rheumatoid arthritis, constituting a possible target for antigen-specific immunotherapy. We addressed the possibility of blocking antigen presentation of the type II co...

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Veröffentlicht in:Arthritis research & therapy 2006-05, Vol.8 (4), Article R93
Hauptverfasser: von Delwig, Alexei, Hilkens, Catharien MU, Altmann, Daniel M, Holmdahl, Rikard, Isaacs, John D, Harding, Clifford V, Robertson, Helen, McKie, Norman, Robinson, John H
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Sprache:eng
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