Dose-related effects of formoterol on airway responsiveness to adenosine 5'-monophosphate and histamine

Inhaled short-acting beta2-agonists provide greater protection against airway responsiveness (AR) to the mast-cell stimulus, adenosine 5'-monophosphate (AMP), than to histamine, a direct spasmogen. Both terbutaline and albuterol exhibit this mast-cell stabilizing property in a dose-dependent ma...

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Veröffentlicht in:	The European respiratory journal 2002-04, Vol.19 (4), p.611-616
Hauptverfasser:	Ketchell, R.I, Jensen, M.W, Spina, D, O'Connor, B.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Monophosphate Adrenergic beta-Agonists - administration & dosage Adrenergic beta-Agonists - pharmacology Adult Airway Resistance - drug effects Biological and medical sciences Bronchial Provocation Tests Bronchoconstriction - drug effects Cross-Over Studies Dose-Response Relationship, Drug Double-Blind Method Ethanolamines - administration & dosage Ethanolamines - pharmacology Female Formoterol Fumarate Histamine Humans Male Mast Cells - drug effects Medical sciences Pharmacology. Drug treatments Respiratory system Terbutaline
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