Development of a Novel Nomogram for Predicting Delayed Methotrexate Excretion in Adult Patients with Hematologic Malignancies

Introduction: High-dose methotrexate (HD-MTX) is an essential regimen for the treatment or prevention of central nervous system disease in hematologic malignancies. However, delayed MTX excretion is a major contributor to increased MTX toxicity and limits its use in populations such as younger indiv...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.4498-4498
Hauptverfasser: Ikeda, Daisuke, Isezaki, Tatsuya, Yuyama, Satoshi, Narita, Kentaro, Oura, Mitsuaki, Uehara, Atsushi, Tabata, Rikako, Takeuchi, Masami, Matsue, Kosei
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Sprache:eng
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