Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged ≥ 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

BACKGROUND: The prognosis of patients with acute myeloid leukemia (AML) varies depending on the presence of mutations in the FLT3 tyrosine kinase. Internal tandem duplications (ITD) and mutations in the tyrosine kinase domain (TKD) result in continuous activation of FLT3, leading to uncontrolled bla...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.2864-2864
Hauptverfasser:	Aspas Requena, Gaspar, Dumas, Pierre Yves, Rodriguez Veiga, Rebeca, Bertoli, Sarah, Gil, Cristina, Simand, Celestine, Ramos-Ortega, Fernando Jesús, Peterlin, Pierre, Serrano, Josefina, Birsen, Rudy, Bernal Del Castillo, Teresa, Tavernier, Emmanuelle, Tormo, Mar, Carre, Martin, Garcia, Maria Jose, Contejean, Adrien, Riaza Grau, Rosalia, Orvain, Corentin, Pérez-Simón, Jose Antonio, Perez Santaolla, Esther, Veronese, Lauren, De Rueda Ciller, Beatriz, Delabesse, Eric, Gutiérrez, Antonio, Mineur, Ariane, De La Fuente Burguera, Adolfo, Guieze, Romain, Pigneux, Arnaud, Montesinos, Pau, Recher, Christian, Matínez-Cuadrón, David
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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