HDAC6 Inhibition Activates Proteasomes to Modulate the MHC Class I Immunopeptidome and Promote Antimyeloma Immunity

The evasion of host immunity is a hallmark of cancer. Tumor cells develop strategies to evade host immunity and to resist currently available immunotherapies, while others present a low tumor mutation burden limiting the presence of tumor antigenicity. Proteasomes are exquisitely complex, intricatel...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.6586-6586
Hauptverfasser:	Rana, Priyanka S., Ignatz-Hoover, James J., Malek, Ehsan, Driscoll, James J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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