RBC eNOS Transduces Regional O2 Gradients to Orchestrate RBC O2 Delivery Phenotype during Circulatory Transit

BACKGROUND: The role of endogenous endothelial NO synthase (eNOS) in mature RBCs is poorly understood. We have previously demonstrated functionally O2-dependent eNOS migration in RBCs, mediating (via s-nitrosylation) glycolytic metabolon assembly/disassembly during circulation in support of antioxid...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.3824-3824
Hauptverfasser:	Safari, Zohreh, Rogers, Stephen C, Brummet, Mary E, Wang, Qihong, Okhuevbie, Joy, Issaian, Aaron, Dzieciatkowska, Monika, Gamboni, Fabia, Held, Jason, D'Alessandro, Angelo, Cortese Krott, Miriam, Doctor, Allan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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