Olutasidenib for the Treatment of mIDH1 Acute Myeloid Leukemia in Patients Relapsed or Refractory to Hematopoietic Stem Cell Transplant, Prior mIDH1 Inhibitor, or Venetoclax

Introduction. Olutasidenib is a small molecule, oral, mutated-IDH1 (mIDH1) inhibitor approved for the treatment of relapsed/refractory (R/R) acute myeloid leukemia (AML). In the pivotal cohort of the registrational phase 1/2 trial, 51/147 (35%) patients achieved a complete remission (CR) or CR with...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.2888-2888
Hauptverfasser: Cortes, Jorge, Jurcic, Joseph, Baer, Maria R., Blum, William, Ferrell, P. Brent, Jonas, Brian A., Lee, Sangmin, Mims, Alice, Patel, Shyam Ajay, Schiller, Gary J., Yang, Jay, Watts, Justin M.
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Sprache:eng
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