TMI-Based Dose-Escalated Bone Marrow Transplantation Can Help Preserve the Bone Marrow Microenvironment and Reduce Cellular Senescence in Old Mice

Introduction:Senescence is one of the hallmarks of aging and age-related conditions, including but not limited to, inflammaging, frailty, and various age-related diseases. It has been well-established that radiation and chemotherapy can accelerate senescence. While myeloablative conditioning-based a...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.3424-3424
Hauptverfasser: Lim, Ji Eun, Sargur Madabushi, Srideshikan, Ghimire, Hemendra, Kimberly K, Richardson, Vishwasrao, Paresh, Abdelhamid, Amr M H, Wong, Jeffrey, Aristei, Cynthia, Kim, Ha-Neui, Zhou, Daohong, Al Malki, Monzr M., Hui, Susanta
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Sprache:eng
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