High Levels of Circulating Granulocytic Myeloid-Derived Suppressor Cells (G-MDSCs) Predict Failure of CD19-Targeting CAR-T Cell Therapy

Background The mechanisms of resistance to CAR-T cell therapy may depend on the physical and biological characteristics of the tumor itself, on CAR-T cells in terms of efficiency and fitness, or on the microenvironment. Myeloid-derived suppressor cells (MDSCs) play a crucial role in hematological tu...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.1015-1015
Hauptverfasser:	Galli, Eugenio, Battaglia, Alessandra, Fossati, Marco, Pansini, Ilaria, Bellesi, Silvia, Buzzonetti, Alexia, Zampetti, Nicole, Hohaus, Stefan, Bacigalupo, Andrea, Chiusolo, Patrizia, Sica, Simona, Fattorossi, Andrea, Sorà, Federica
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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