Multimodal Single-Cell Transcriptomic and Proteomic Correlatives of Patients Outcomes Following Anti-BCMA Cellular Therapy with Ciltacabtagene Autoleucel (Cilta-cel) in Relapsed Multiple Myeloma

Introduction Multimodal single cell technologies allow us to dissect the mechanisms of therapeutic resistance by integrating transcriptomics and proteomics through the combination of antibody labeling and next-generation sequencing. Using CITE-seq, mass cytometry (CyTOF) and quantitative multiplexed...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.93-93
Hauptverfasser:	Vieira dos Santos, Junia, Melnekoff, David, Aleman, Adolfo, Bhalla, Sherry, Mouhieddine, Tarek H., Van Oekelen, Oliver, Rajeeve, Sridevi, Upadhyaya, Bhaskar, Ghodke-Puranik, Yogita, Leshchenko, Violetta, Rahman, Adeeb, Afik, Shaked, Lewinsky, Hadas, Thibaud, Santiago, Cho, Hearn Jay, Richter, Joshua, Rodriguez, Cesar, Sanchez, Larysa, Rossi, Adriana C, Richard, Shambavi, Chari, Ajai, Jagannath, Sundar, Parekh, Samir, Lagana, Alessandro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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