High Efficacy and Excellent Safety Profile of Actalycabtagene Autoleucel, a Humanized CD19 CAR-T Product in r/r B-Cell Malignancies: A Phase II Pivotal Trial

Background: Commercially approved CD19 CAR-T cell therapies are effective in r/r B cell malignancies, but are associated with significant albeit manageable toxicities. These toxicities contribute to significant morbidity. We have developed a novel, humanized CD19 CAR-T cell therapy, Actalycabtagene...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.4838-4838
Hauptverfasser:	Jain, Hasmukh, Karulkar, Atharva, Kalra, Devanshi, Ravikumar, Smrithi, Ghandade, Netra, Patil, Ruchira, Shah, Shreshtha, Firfiray, Afrin, Pendhari, Juber, Patil, Rushikesh, S, Manivasagam, Sharma, Neha, Shetty, Alok, Nayak, Lingaraj, Bagal, Bhausaheb, Banavali, Shripad, Narula, Gaurav, Desai, Preeti, Navkudkar, Anisha, Tembhare, Prashant, Khattry, Navin, Sridhar, Epari, Patkar, Nikhil, Gujral, Sumeet, Shet, Tanuja, Sakhadeo, Uma, Subramanian, Papagudi Ganesan, Thorat, Jayshree, Prashant, Anamika, Punatar, Sachin, Gokarn, Anant, Ghosh, Kinjalka, Agrawal, Archi, Jain, Yash, Rangarajan, Venkatesh, Ojha, Shashank, Bhosle, Shilpushp, Laskar, Siddhartha, Kakoti, Sangeeta, Mirgh, Sumeet, Hiregoudar, Sumathi, Poojary, Minal, Shetty, Nitin, Patil, Vasundhara, Baheti, Akshay, Biswas, Sanjay, Salunkhe, Gaurav, Gala, Kunal, Sengar, Manju, Shah, Nirali N., Neelapu, Sattva S., Purwar, Rahul
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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