HGF Regulation in the Tumor-Supportive Microenvironment Combined with Pan-PIM Kinases Inhibition in Malignant Cells As a Multi-Target Approach for Acute Myeloid Leukemia

Background: In acute myeloid leukemia (AML), persistent clonal proliferation of malignant myeloid cells results in high severity and low cure potential. Resistance to currently available chemotherapeutics and disease relapse remains an important concern worldwide. Several molecular targets play key...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.3641-3641
Hauptverfasser: Roversi, Fernanda Marconi, Bueno, Maura Lima Pereira, Niemann, Fernanda Soares, Santos, Irene, Amôr, Nádia Ghinelli, Santos, Adriana Duarte da Silva, Bastos, Audrey, Saad, Sara Teresinha Olalla
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Sprache:eng
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