Prediction Modeling of CAR-T Cell Therapy for Diffuse Large B-Cell Lymphoma Using Artificial Neural Networks on Tumor Vascular Phenotype

Chimeric antigen receptor T (CAR-T) cell therapy targeting CD19 only results in complete remission in approximately 30-40% of relapsed/refractory disease patients with diffuse large B-cell lymphoma (DLBCL). Failure may result from lack of CAR-T entry into the tumor. Endogenous T cell homing is initi...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.2075-2075
Hauptverfasser: Verma, Anuj, Liburd, Samuel, Tobias, Zsuzsanna, Isufi, Iris, Pober, Jordan, Xu, Mina L
Format: Artikel
Sprache:eng
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