Combination of Decitabine and Etoposide Is Highly Effective in Treating p53-Mutated MDS/AML Via Activating Notch Signaling

The elderly MDS/AML patients, especially those with TP53 mutations, remain very difficult to treat and resistant to chemotherapy. A total of 105 elderly (age above 60 years) high risk MDS (n = 84, IPSS-R score > 4.5) or AML-MRC (n = 21) patients' records were collected from three medical cen...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.4131-4131
Hauptverfasser:	Ma, Jiexian, Sun, Shunrong, Wu, Min, Zuo, Xinyu, Xie, Mixue, Wang, Xiaoqin, Ye, Xiu-Jin, Shen, Shuhong, Xie, Yanhui
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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