Single Cell Profiling Unravels Plasma Cell Gene Expression Signatures Predictive of Response to Daratumumab Based Therapy, and Prognosis in Multiple Myeloma

Background: Multiple Myeloma (MM) is the second most common hematologic malignancy and remains incurable. Daratumumab (dara) is a potent anti-CD38 monoclonal antibody used for MM treatment, but responses are heterogeneous, and resistance is inevitable. There is hence an urgent need for biomarkers to...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.3367-3367
Hauptverfasser:	Scolnick, Jonathan, Xu, Stacy, Soekojo, Cinnie, Song, Fangfang, Ooi, Melissa, Nagarajan, Chandramouli, Chng, Wee-Joo, De Mel, Sanjay
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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