Biomarker Correlates of Response to Ciltacabtagene Autoleucel in Patients with Relapsed or Refractory Multiple Myeloma from CARTITUDE-1, a Phase 1b/2 Open-Label Study, at the ~3 Year Follow-up

Ciltacabtagene autoleucel (cilta-cel) consists of autologous T cells genetically modified to express a two-binding domain chimeric antigen receptor (CAR). The target antigen of the CAR is B-cell maturation antigen (BCMA), which is highly expressed on malignant plasma cells (PC) from multiple myeloma...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.2099-2099
Hauptverfasser: Montes de Oca, Rocio, Gu, Junchen, Zhao, Hao, Zelinsky, Kathy, Wu, Dianna, Davis, Cuc, Patel, Jaymala, Foulk, Brad, Boominathan, Rengasamy, Lau, Onsay, Smirnov, Denis, Lin, Yi, Jagannath, Sundar, Cohen, Adam D., Haddish-Berhane, Nahor, Xu, Jean, Madduri, Deepu, Stevens, An-Sofie, Jackson, Carolyn Chang, Schecter, Jordan M., Banerjee, Arnob, Geng, Dong, Zhu, Jieqing, Xu, Sifan, Zudaire, Enrique
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Sprache:eng
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