Combination of Propranolol and a Novel CXCR4 Antagonist Burixafor (GPC-100) for Enhanced Hematopoietic Cell Mobilization

Burixafor (GPC-100), a novel CXCR4 antagonist, has shown safe and effective mobilization of hematopoietic stem and progenitor cells (HSPC) in a phase I clinical study. In multiple myeloma patients, GPC-100 combined with granulocyte-colony stimulating factor (G-CSF) elicited a significant increase in...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.3428-3428
Hauptverfasser:	Sukhtankar, Devki D., Cayton, Thomas, Zalicki, Piotr, Choi, Junhee, Mun, Seonggyeong, Jo, Yoonjung, Kim, Sujeong, Lee, Ji Yeong, Kim, Mi-Na, Chin, Ashley, Ramos, Christian, Huh, Won-Ki, Kim, Sohui, Caculitan, Nina, Jeong, Jae-Yeon, Cardarelli, Josephine M.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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