Efficient and Specific In Vivo Genetic Engineering of Human Hematopoietic Stem Progenitor Cells without Selective Conditioning

Achieving in vivo genetic engineering of hematopoietic stem progenitor cells (HSPC) has the potential to transform treatment for hematological disorders. An ideal in vivo delivery platform should provide access to resting HSPC at low doses, in different in vivo compartments and with high specificity...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.2252-2252
Hauptverfasser: Botchkarev, Vladimir V, Harrington, Sean, Justen, Alexander, Kimber, Casey, Kapuria, Anjali, Xu, Yuanxin, Haugh, Kelsey, Ankala, Ramya, Kipniss, Nathan, de Jesus, Rowena, Adewale, Funmi, Daniels, Kathy, Crocker, Samantha, Liang, Anna, Joyce, Shannon, Smith, Derek, Wong, Athena, Berlfein, Valeria, Amatya, Shirisha, Cruite, Patricia, Usmani, Shariq, Ruzo, Albert, Ferland, Benjamin, Chandra, Sundeep, Stoppato, Matteo, Trudeau, Kyle, Rebar, Edward, Shah, Jagesh, Biasco, Luca
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Sprache:eng
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