Phase 1/2a Trial of Bomedemstat with or without All- Trans Retinoic Acid (ATRA) in Advanced Myeloid Malignancies

Background: Acute myeloid leukemia (AML) is a devastating disease difficult to treat. Although > 60% of patients (pts) with AML treated with standard therapy achieve complete remission, at least 70% relapse. Overexpression of lysine-specific demethylase 1 (LSD1) mRNA and excess LSD1 protein have...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.6494-6494
Hauptverfasser:	Ross, David M., Stevenson, William S., Shortt, Jake, Cooney, Julian, Lewis, Ian, Rienhoff Jr, Hugh Young
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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