A Novel and Potent EZH1/2 Dual Inhibitor, HM97662 Demonstrated a Wide Spectrum of Therapeutic Potential for Hematological Malignancies

Chromatin remodeling is a crucial process for transcriptional regulation, of which dysregulation is often observed in various human cancers. The enhancer of zeste homolog 2 (EZH2) and its homolog EZH1 are catalytic components of polycomb repressive complex 2 (PRC2), which tri-methylate histone H3 at...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.7134-7134
Hauptverfasser:	Jung, Seung Hyun, Byun, Jooyun, Kim, Yu-Yon, Han, Seon Yeong, Lee, Miyoung, Lee, Gunwoo, Park, Junghwa, Ahn, Young Gil, Kim, Young Hoon, Suh, Kwee Hyun, Koh, Youngil
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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