Combined Single-Cell and Spatial Transcriptomics Unveil the Complex Organization of the Non-Immune Human Bone Marrow Microenvironment during Aging

Hematopoietic stem cells (HSCs), reside in a specialized bone marrow (BM) microenvironment known as the hematopoietic stem niche. Despite the critical role of the niche in tightly controlling the processes of normal and malignant hematopoiesis, its cellular composition remains only partially underst...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.2706-2706
Hauptverfasser:	Cenzano, Itziar, Cocera, Miguel, Lehmann, Robert, Ye, Jin, Vilas-Zornoza, Amaia, San-Martin, Patxi, Aguirre-Ruiz, Paula, Alignani, Diego, Lopez, Aitziber, Paiva, Bruno, Miñana Barrios, Marta, Sancho Gonzalez, Ignacio, Ruiz, Javier, Sarvide, Sarai, Ripalda-Cemborain, Purificacion, Sudupe, Laura, Muiños-Lopez, Emma, Lagani, Vincenzo, Tegner, Jesper, Saez-Ochoa, Borja, Calvo, Isabel A, Gomez-Cabrero, David, Prosper, Felipe
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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