Lymphoma-Derived IL-10 Is a Key Immunomodulatory Factor at the Tumor Microenvironment of Activated B-Cell Diffuse Large B-Cell Lymphoma and Influences In Vivo Responses to Immunotherapy

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of aggressive non-Hodgkin's lymphoma with ~40% of patients experiencing refractory or relapsed disease to R-CHOP immunochemotherapy. These higher risk patients often exhibit gene expression profiles that resemble a late germinal c...

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Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 1), p.716-716
Hauptverfasser:	Garcia-Lacarte, Marcos, Grijalba, Sara C, Novo, Francisco J, Arnaiz-Leché, Adrián, Melchor, Javier, Pascual, Marién, Goñi, Enrique, Morales-Sánchez, Sandra, Burrell, María A, Blanco, Oscar, Clemente-Larramendi, Iñigo, Martinez-Climent, Jose A, Casares, Noelia, Lasarte, Juan J, Sarobe, Pablo, Canales, Miguel, Roa, Sergio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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