Janus Kinase (JAK) 1 Inhibition Results in Significant Changes in Serum Proteins and Peripheral T-Cell Populations That Correlated with Clinical Scores in Chronic Graft Versus Host Disease (GVHD) Patients (an Analysis from GRAVITAS-309)

Background: Chronic GVHD (cGVHD) occurs in 30-70% of allogeneic hematopoietic cell transplantation patients, and the rate has increased over the past 2 decades. Based on the degree of organ involvement, cGVHD is classified as mild, moderate, or severe. Standard treatment includes systemic corticoste...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.2197-2197
Hauptverfasser: Pratta, Michael, Volkova, Angelina, Bleam, Maureen, Morariu-Zamfir, Rodica, Rumberger, Beth, Douglass, Stephen, Smith, Susan H., Bhatt, Valkal, Galvin, John, Im, Annie, Paczesny, Sophie, Schultz, Kirk R., Pavletic, Steven Z.
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Sprache:eng
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