The Real-World Outcomes of Ponatinib in 724 Patients with CML and Ph + ALL : A Post-Marketing Surveillance Study with a Special Interest in Arterial Occlusive Events in Japan

Introduction Ponatinib inhibits the BCR::ABL1 kinase, including a variant with threonine-to-isoleucine at position 315 (T315I) (Cortes et al. N Eng J Med. 2013; 369:1783-96); however, it has been reported that ponatinib is associated with a higher risk of major arterial events than other TKIs among...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.4537-4537
Hauptverfasser: Takahashi, Naoto, Kondo, Takeshi, Ikari, Yuji, Fukumoto, Yoshihiro, Hatake, Kiyohiko, Masunari, Akira, Nishibayashi, Seiji, Kageyama, Akiko, Fukuta, Yasuhiko, Tojo, Arinobu
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Sprache:eng
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