Obesity-Induced Inflammation Co-Operates with Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutants to Promote Leukemia Development and Cardiovascular Disease

▪ Obesity is an increasing epidemic world-wide responsible for enhancing the risk for developing Type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD) and cancer. However, it is unclear if and how obesity contributes to the transformation of pre-leukemic stem and progenitors (pre-LHSC/Ps) in...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.1094-1094
Hauptverfasser:	Pasupuleti, Santhosh Kumar, Ramdas, Baskar, Burns, Sarah S., Kumar, Ramesh, Pandhiri, Taruni Reddy, Sandusky, George, Yu, Zhi, Honigberg, Michael, Bick, Alexander G., Griffin, Gabriel K., Niroula, Abhishek, Ebert, Benjamin L., Natarajan, Pradeep, Kapur, Reuben
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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