Structure-Activity Relationship Analysis of Analogs of Rhosin, a RhoA Inhibitor, Reveals a New Generation of Improved Antiplatelet Agents

Platelet activation and aggregation play a key role in mediating hemostasis and thrombosis. The antiplatelet therapies currently available in the market are associated with a high risk of hemorrhage and are mostly irreversible in suppressing platelet activity; hence, there is a need to develop bette...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.3989-3989
Hauptverfasser:	Dandamudi, Akhila, Seibel, William, Akbar, Huzoor, Zheng, Yi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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