Lymphocyte Cytosolic Protein 1 I232F Mutation Impairs Granulocytic Proliferation with a G2/M Block in Severe Neutropenia

▪ Introduction: As critical effectors of innate immune response, neutrophils migrate from the vasculature into inflamed tissue, where they engage in phagocytosis and clearance of pathogens and apoptotic cells. Migration, phagocytosis, and granule release require multiple well-coordinated events invo...

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Veröffentlicht in:Blood 2021-11, Vol.138 (Supplement 1), p.434-434
Hauptverfasser: Mahat, Upendra, Garg, Bhavuk, Mehta, Hrishikesh M, Rogers, Heesun J., Ivanov, Andrei, Yang, Chao-Yie, Flagg, Aron, Corey, Seth J.
Format: Artikel
Sprache:eng
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