The Autocrine Secreted PDZD2 Functions As a Novel Tumor Suppressor in AML, Inducing Growth Inhibition and Cell Cycle Arrest

Epigenetic deregulation is a hallmark of acute myeloid leukemia (AML) and we have previously reported that recurring epigenetic abnormalities can be found across all AML subtypes, irrespective of cytogenetic or molecular drivers. Among the genes recurrently hypermethylated in AML we identified PDZD2...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.3320-3320
Hauptverfasser:	Guerrero Schimpf, Marlise L, Figueroa, Maria E.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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