Identification of a Novel Epigenetic Mechanism of MYC Deregulation in Smoldering and Newly Diagnosed Multiple Myeloma Patients

Enhanced expression of the MYC oncogene is associated with the initiation and maintenance of many human cancers, including multiple myeloma (MM). MM is a malignancy of clonal plasma cells, in which MYC deregulation is a key event in the progression from the precursor stages of monoclonal gammopathy...

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Veröffentlicht in:Blood 2021-11, Vol.138 (Supplement 1), p.504-504
Hauptverfasser: Rahmat, Mahshid, Clement, Kendell, Sklavenitis-Pistofidis, Romanos, Kodgule, Rohan, Fulco, Charles, Alberge, Jean-Baptiste, Boehner, Cody J., Agius, Michael P., Kitzenberg, Elizabeth Morgan, Dorfman, David, Ryan, Russell J.H., Pinello, Luca, Ghobrial, Irene M.
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Sprache:eng
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