Single-Cell Multi-Omic Analysis Uncovers Comprised Immune Function and Primary Resistance Mechanism in Acute Myeloid Leukemia

Background: Approximately 20% of AML patients do not respond to induction chemotherapy (primary resistance) and 40-60% of patients develop secondary resistance, eventually leading to relapse followed by refractory disease (RR-AML). Diversified molecular mechanisms have been proposed for drug resista...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.378-378
Hauptverfasser:	Zhou, Jianbiao, Scolnick, Jonathan Adam, Xu, Stacy, Ooi, Melissa, Chia, Priscella Shirley, Toh, Sabrina Hui-Min, Balan, Kalpnaa, Lovci, Michael, Tan, Tuan Zea, Ying, Jen Wei, NG, Chin-Hin, Chng, Wee-Joo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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