Clinical and Biological Effects of Combined CD27 and CD20 Antibody Therapy in Relapsed/Refractory B-Cell Lymphoma: The Riva Trial

Background: CD27 antibody stimulation of T cells has been shown to activate and promote myeloid cell infiltration leading to enhanced antibody-dependent cellular phagocytosis (ADCP) by anti-CD20 in lymphoma preclinical models (Turaj et al Cancer Cell 2017). In this phase IIa study (RiVa NCT03307746)...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.715-715
Hauptverfasser:	Lim, Sean H, Sow, Heng Sheng, Wignall, Christopher, Mercer, Katy, Caddy, Josh, Boxall, Cherish, Thorne, Kerensa, Northey, Joshua, Stanton, Louise, Konn, Zoë, Fines, Keira, Medd, Patrick G., Coleman, Adam, Nunn, Lorna, Lown, Robert, McKay, Pamela, Osborne, Wendy, Linton, Kim, Collins, Graham P., Gentles, Andrew J, Rose-Zerilli, Matthew, Griffiths, Gareth
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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