Pharmacokinetics and Pharmacodynamics of Recombinant FIX Variants in the FIX Knockout Mouse Tail Clip Bleeding Model

Introduction: The recessive X-linked bleeding disorder Hemophilia B is caused by a mutation in the coagulation factor (F) IX gene leading to partial or total loss of its function. Preventive treatment with replacement long-acting FIX is an attractive option for patients to reduce administration freq...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.3180-3180
Hauptverfasser:	Pestel, Sabine, Peil, Hendrik, Knoll Machado, Steffi, Claar, Philipp, Raquet, Elmar, Ponnuswamy, Padmapriya, Mischnik, Marcel, Ghobrial, Oliver, Herzog, Eva
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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