High Rates of Remission with the Initial Treatment of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL): Clinical Outcomes and Biomarker Analysis of a Multi-Center Phase II Study

▪ Nodal PTCL with T-follicular helper phenotype (PTCL-TFH), which includes angioimmunoblastic T-cell lymphoma, is characterized by recurrent mutations affecting epigenetic regulators. Azacitidine, a DNA demethylating agent, has shown clinical activity as a single agent and in combination in R/R PTCL...

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Veröffentlicht in:	Blood 2021-11, Vol.138 (Supplement 1), p.138-138
Hauptverfasser:	Ruan, Jia, Moskowitz, Alison J., Mehta-Shah, Neha, Sokol, Lubomir, Chen, Zhengming, Rahim, Riyaad, Song, Wei, Kotlov, Nikita, Nos, Grigorii, Maksimov, Vladislav, Revuelta, Maria Victoria, Sboner, Andrea, Sigouros, Michael, van Besien, Koen, Horwitz, Steven M., Rutherford, Sarah C., Mulvey, Erin C., Coleman, Morton, Melnick, Ari, Elemento, Olivier, Inghirami, Giorgio, Leonard, John P., Martin, Peter, Cerchietti, Leandro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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