Predicting Resistance to the Combination of ATO and ATRA in APL Patients with PML-Rara Fusions, Using a Computational Biology Modeling Approach: Mycare-021-01

Background: Acute promyelocytic leukemia (APL) is a biologically and clinically distinct subtype of acute myeloid leukemia (AML) with unique molecular pathogenesis, clinical manifestations, and treatment. APL is cytogenetically characterized by a balanced translocation t(15;17) (q24;q21), which invo...

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Veröffentlicht in:Blood 2020-11, Vol.136 (Supplement 1), p.31-32
Hauptverfasser: Howard, Scott, Nair, Prashant Ramachandran, Grover, Himanshu, Tyagi, Anuj, Kumari, Pallavi, Prasad, Samiksha Avinash, Mitra, Upasana, Lala, Deepak Anil, Azam, Humera, Gupta, Neha, Mohapatra, Subrat, G, Poornachandra, Mundkur, Nirjhar, Macpherson, Michele Dundas, Kapoor, Shweta
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Sprache:eng
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