PD-L1 Pathway Markers and Chromosome 9p24.1 Alterations in Patients with Classic Hodgkin Lymphoma Treated with Frontline Single Agent Pembrolizumab (PEM) Followed By AVD Chemotherapy

Background: Chromosome 9p24.1/PD-L1/PD-L2 genomic copy number alterations (CNAs) including amplifications and copy number gains (CNGs) are predominant features of classic Hodgkin lymphoma (cHL) and lead to overexpression of the programmed death-1 (PD-1) ligands 1 and 2 (PD-L1 and PD-L2). Amplificati...

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Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.17-18
Hauptverfasser:	Allen, Pamela B., Lu, Xinyan, Chen, Qing C, Barnea Slonim, Liron, Sukhanova, Madina, Savas, Hatice, Chmiel, Joan, O'Shea, Kaitlyn, Evens, Andrew M., Advani, Ranjana, Pro, Barbara, Karmali, Reem, Palmer, Brett Alan, Bearden, Jeffrey, Mou, Eric, Dillehay, Gary, Gordon, Leo I., Winter, Jane N.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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