Reduced-Intensity Chemotherapy with Mini-Hyper-CVD Plus Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: Results from a Phase II Study

Background: Inotuzumab ozogamicin (INO) and blinatumomab both improve overall survival (OS) in relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). Use of these effective monoclonal antibodies in the frontline setting may lead to deep and durable remissions in older adults with newly di...

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Veröffentlicht in:Blood 2020-11, Vol.136 (Supplement 1), p.15-17
Hauptverfasser: Short, Nicholas J., Kantarjian, Hagop M., Ravandi, Farhad, Huang, Xuelin, Jain, Nitin, Kadia, Tapan M., Khoury, Joseph D., Jorgensen, Jeffrey L., Wang, Sa A, Alvarado, Yesid, Burger, Jan A., Daver, Naval, Borthakur, Gautam, DiNardo, Courtney D., Konopleva, Marina, Pemmaraju, Naveen, Garcia-Manero, Guillermo, Wierda, William G., Kornblau, Steven M., Jacob, Jovitta, Rostykus, Meagan, Kwari, Monica, Rausch, Caitlin R., Loiselle, Christopher, Milton, Anna, Rivera, Juan, Garris, Rebecca, O'Brien, Susan M., Jabbour, Elias
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Sprache:eng
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