Cpi-818, an Oral Interleukin-2-Inducible T-Cell Kinase Inhibitor, Is Well-Tolerated and Active in Patients with T-Cell Lymphoma

Background: Interleukin-2-Inducible T-Cell Kinase (ITK) is a Tec-family, non-receptor tyrosine kinase expressed in T-cells that plays a key role in T-cell receptor (TCR) signaling, which is required for development and differentiation of T-cells. In T-cell lymphoproliferative disorders, expression o...

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Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.19-20
Hauptverfasser:	Khodadoust, Michael S., Feldman, Tatyana A., Yoon, Dok Hyun, Yannakou, Costas K., Radeski, Dejan, Kim, Youn H., Mehta-Shah, Neha, Khot, Amit, Wilcox, Ryan A., Kim, Won Seog, Horwitz, Steven M., Buggy, Joseph J., Hotson, Andrew, Hill, Craig M., Munneke, Brian, Mahabhashyam, Suresh, Miller, Richard A., Janc, James W., Mobasher, Mehrdad
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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