B-CLL Mediated Resistance to CAR T Cell Therapy Via Insufficient Activation Is CAR-Independent

Chronic Lymphocytic Leukemia (CLL) is a B cell malignancy that accounts for nearly 1/3rd of adult leukemia diagnoses in the Western world. Conventional chemo-immunotherapies initially control progression, but in the absence of curative options patients ultimately succumb to their disease. Chimeric A...

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Veröffentlicht in:Blood 2020-11, Vol.136 (Supplement 1), p.44-44
Hauptverfasser: Collins, McKensie, Kong, Weimin, Jung, Inyoung, Lundh, Stefan M, Melenhorst, J. Joseph
Format: Artikel
Sprache:eng
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