Phase Ib Study of Ianalumab (VAY736) and Ibrutinib in Patients with Chronic Lymphocytic Leukemia (CLL) on Ibrutinib Therapy

Introduction: B cell activating factor receptor (BAFF-R) promotes the maturation and survival of normal and malignant B cells. VAY736 is a human investigational Fc-engineered afucosylated monoclonal antibody (mAb) targeting BAFF-R and enhancing NK-cell mediated antibody-dependent cellular cytotoxici...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.13-14
Hauptverfasser:	Rogers, Kerry A., Flinn, Ian W., McGarry, Carolyn, Gou, Liangke Connie, Hassounah, Nadia, Woo, Janghee, Byrd, John C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!