Venetoclax Crosses the Blood Brain Barrier: A Pharmacokinetic Analysis of the Cerebrospinal Fluid in Pediatric Leukemia Patients

Introduction: Venetoclax is a selective BCL2 inhibitor approved for the treatment of CLL and AML in adults and is currently being evaluated in several hematologic and solid malignancies. While plasma pharmacokinetics (PK) of venetoclax is well documented, data regarding the accumulation of venetocla...

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Veröffentlicht in:	Blood 2020-11, Vol.136 (Supplement 1), p.30-31
Hauptverfasser:	Salem, Ahmed Hamed, Badawi, Mohamed A, Place, Andrew E., Palenski, Tammy L., Arrendale, Richard, Kim, Su Young, Federico, Sara, Cooper, Todd M., Menon, Rajeev
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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