Mutated Cancer-Related Genes Detected at Diagnosis of CML and a Novel Class of Variant Associated with the Philadelphia Translocation Are Both Independent Predictors of Inferior Outcomes

▪ Background We previously reported a high incidence of mutated cancer-related genes at CML diagnosis in selected chronic phase patients with a poor outcome compared to those with a good outcome. We also found a novel class of variant associated with the formation of the Ph chromosome comprising fus...

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Veröffentlicht in:Blood 2020-11, Vol.136 (Supplement 1), p.46-47
Hauptverfasser: Shanmuganathan, Naranie, Wadham, Carol, Shahrin, Nur Hezrin, Thomson, Daniel, Feng, Jinghua, Saunders, Verity A, Lin, Ming, Kenyon, Rosalie, King, Rob, Wang, Paul, Ross, David M, Yeung, David T, Schreiber, Andreas W, Hughes, Timothy P., Branford, Susan
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Sprache:eng
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